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PUBLICATIONS

For a complete listing, you can also check here (Google Scholar) or here (Pubmed).

1.    Steiner BM, Benvie AM, Lee D, Jiang Y, Berry DC. Cxcr4 regulates a pool of adipocyte progenitors and contributes to adiposity in a sex-dependent manner. Nat Commun. 2024;15(1):6622. Epub 20240805. doi: 10.1038/s41467-024-50985-8. PubMed PMID: 39103342; PMCID: PMC11300861.

2.    Yuan Y*, Hu R*, Park J*, Xiong S, Wang Z, Qian Y, Shi Z, Wu R, Han Z, Ong SG, Lin S, Varady KA, Xu P, Berry DC, Shu G, Jiang Y#. Macrophage-derived chemokine CCL22 establishes local LN-mediated adaptive thermogenesis and energy expenditure. Sci Adv. 2024;10(26):eadn5229. Epub 20240626. doi: 10.1126/sciadv.adn5229. PubMed PMID: 38924414.

3.    Park J*, Hu R*, Qian Y, Xiong S, El-Sabbagh AS, Ibrahim M, Wang J, Xu Z, Chen Z, Song Q, Song Z, Yan G, Mahmoud AM, He Y, Layden BT, Chen J, Ong SG#, Xu P#, Jiang Y#. Estrogen counteracts age-related decline in beige adipogenesis through the NAMPT-regulated ER stress response. Nat Aging. 2024;4(6):839-53. Epub 20240610. doi: 10.1038/s43587-024-00633-z. PubMed PMID: 38858606.

4.    Ye H, Yang X, Feng B, Luo P, Torres Irizarry VC, Carrillo-Saenz L, Yu M, Yang Y, Eappen BP, Munoz MD, Patel N, Schaul S, Ibrahimi L, Lai P, Qi X, Zhou Y, Kota M, Dixit D, Mun M, Liew CW, Jiang Y, Wang C#, He Y#, Xu P#. 27-Hydroxycholesterol acts on estrogen receptor alpha expressed by POMC neurons in the arcuate nucleus to modulate feeding behavior. Sci Adv. 2024;10(28):eadi4746. Epub 20240712. doi: 10.1126/sciadv.adi4746. PubMed PMID: 38996023; PMCID: PMC11244552.

5.    Lee D, Benvie AM, Steiner BM, Kolba NJ, Ford JG, McCabe SM, Jiang Y, Berry DC. Smooth muscle cell-derived Cxcl12 directs macrophage accrual and sympathetic innervation to control thermogenic adipose tissue. Cell Rep. 2024;43(5):114169. Epub 20240427. doi: 10.1016/j.celrep.2024.114169. PubMed PMID: 38678562.

6.    Shi Z, Xiong S, Hu R, Wang Z, Park J, Qian Y, Wang J, Bhalla P, Velupally N, Song Q, Song Z, Jeon MS, Zhang KK, Xie L, Layden BT, Ong SG, Jiang Y#. The Notch-PDGFRbeta axis suppresses brown adipocyte progenitor differentiation in early post-natal mice. Dev Cell. 2024. Epub 20240326. doi: 10.1016/j.devcel.2024.03.012. PubMed PMID: 38569546.

7.    Munoz M, Solis C, McCann M, Park J, Rafael-Clyke K, Chowdhury SAK, Jiang Y, Rosas PC. P21-activated kinase-1 signaling is required to preserve adipose tissue homeostasis and cardiac function. Mol Cell Biochem. 2024. Epub 20240302. doi: 10.1007/s11010-024-04968-4. PubMed PMID: 38430300.

8.    Song Q, Hwang CL, Li Y, Wang J, Park J, Lee SM, Sun Z, Sun J, Xia Y, Nieto N, Cordoba-Chacon J, Jiang Y, Dou X, Song Z. Gut-derived ammonia contributes to alcohol-related fatty liver development via facilitating ethanol metabolism and provoking ATF4-dependent de novo lipogenesis activation. Metabolism. 2024;151:155740. Epub 20231122. doi: 10.1016/j.metabol.2023.155740. PubMed PMID: 37995805.

9.    Benvie AM, Lee D, Jiang Y, Berry DC. Platelet-derived growth factor receptor beta is required for embryonic specification and confinement of the adult white adipose lineage. iScience. 2024;27(1):108682. Epub 20231212. doi: 10.1016/j.isci.2023.108682. PubMed PMID: 38235323; PMCID: PMC10792241.

10.    Yuan Y*, Shin S*, Shi Z, Shu G, Jiang Y#. Postnatal Tamoxifen Exposure Induces Long-Lasting Changes to Adipose Tissue in Adult Mice. Mol Biotechnol. 2023. Epub 20230829. doi: 10.1007/s12033-023-00828-6. PubMed PMID: 37642828.

11.    Yuan Y*, Shi Z*, Xiong S*, Hu R, Song Q, Song Z, Ong SG, Jiang Y#. Differential roles of insulin receptor in adipocyte progenitor cells in mice. Mol Cell Endocrinol. 2023:111968. Epub 20230525. doi: 10.1016/j.mce.2023.111968. PubMed PMID: 37244600.

12.    Wu R*, Park J*, Qian Y, Shi Z, Hu R, Yuan Y, Xiong S, Wang Z, Yan G, Ong SG, Song Q, Song Z, Mahmoud AM, Xu P, He C, Arpke RW, Kyba M, Shu G, Jiang Q, Jiang Y#. Genetically prolonged beige fat in male mice confers long-lasting metabolic health. Nat Commun. 2023;14(1):2731. Epub 20230512. doi: 10.1038/s41467-023-38471-z. PubMed PMID: 37169793; PMCID: PMC10175245.

13.    Benvie AM, Lee D, Steiner BM, Xue S, Jiang Y, Berry DC. Age-dependent Pdgfrbeta signaling drives adipocyte progenitor dysfunction to alter the beige adipogenic niche in male mice. Nat Commun. 2023;14(1):1806. Epub 20230331. doi: 10.1038/s41467-023-37386-z. PubMed PMID: 37002214; PMCID: PMC10066302.

14.    Song Q, Chen Y, Ding Q, Griffiths A, Liu L, Park J, Liew CW, Nieto N, Li S, Dou X, Jiang Y, Song Z. mTORC1 inhibition uncouples lipolysis and thermogenesis in white adipose tissue to contribute to alcoholic liver disease. Hepatol Commun. 2023;7(3):e0059. Epub 20230209. doi: 10.1097/HC9.0000000000000059. PubMed PMID: 36757400.

15.    Torres Irizarry VC, Jiang Y#, He Y#, Xu P#. Hypothalamic Estrogen Signaling and Adipose Tissue Metabolism in Energy Homeostasis. Front Endocrinol (Lausanne). 2022;13:898139. Epub 2022/06/28. doi: 10.3389/fendo.2022.898139. PubMed PMID: 35757435; PMCID: PMC9218066.

16.    Yuan Y, Zhu C, Wang Y, Sun J, Feng J, Ma Z, Li P, Peng W, Yin C, Xu G, Xu P, Jiang Y, Jiang Q, Shu G. alpha-Ketoglutaric acid ameliorates hyperglycemia in diabetes by inhibiting hepatic gluconeogenesis via serpina1e signaling. Sci Adv. 2022;8(18):eabn2879. Epub 2022/05/05. doi: 10.1126/sciadv.abn2879. PubMed PMID: 35507647; PMCID: PMC9067931.

17.    Wang Z, Kim J, Zhang P, Galvan Achi JM, Jiang Y, Rong L. Current therapy and development of therapeutic agents for lung cancer. Cell Insight. 2022;1(2):100015. doi: https://doi.org/10.1016/j.cellin.2022.100015.

18.    Ye H, Feng B, Wang C, Saito K, Yang Y, Ibrahimi L, Schaul S, Patel N, Saenz L, Luo P, Lai P, Torres V, Kota M, Dixit D, Cai X, Qu N, Hyseni I, Yu K, Jiang Y, Tong Q, Sun Z, Arenkiel BR, He Y, Xu P, Xu Y. An estrogen-sensitive hypothalamus-midbrain neural circuit controls thermogenesis and physical activity. Sci Adv. 2022;8(3):eabk0185. Epub 2022/01/20. doi: 10.1126/sciadv.abk0185. PubMed PMID: 35044814; PMCID: PMC8769556.

19.    Wang Z, Peet NP, Zhang P, Jiang Y, Rong L. Current Development of Glioblastoma Therapeutic Agents. Mol Cancer Ther. 2021;20(9):1521-32. Epub 2021/06/27. doi: 10.1158/1535-7163.MCT-21-0159. PubMed PMID: 34172531.

20.    Park J*, Shin S*, Liu L*, Jahan I, Ong SG, Xu P, Berry DC, Jiang Y#. Progenitor-like characteristics in a subgroup of UCP1+ cells within white adipose tissue. Dev Cell. 2021;56(7):985-99 e4. Epub 2021/03/13. doi: 10.1016/j.devcel.2021.02.018. PubMed PMID: 33711247; PMCID: PMC8026751.

21.    Paris S, Ekeanyanwu R, Jiang Y, Davis D, Spechler SJ, Souza RF. Obesity and its effects on the esophageal mucosal barrier. Am J Physiol Gastrointest Liver Physiol. 2021;321(3):G335-G43. Epub 2021/08/19. doi: 10.1152/ajpgi.00199.2021. PubMed PMID: 34405732.

22.    Griffiths A, Wang J, Song Q, Iyamu ID, Liu L, Park J, Jiang Y, Huang R, Song Z. Nicotinamide N-methyltransferase upregulation via the mTORC1-ATF4 pathway activation contributes to palmitate-induced lipotoxicity in hepatocytes. Am J Physiol Cell Physiol. 2021;321(3):C585-C95. Epub 2021/08/12. doi: 10.1152/ajpcell.00195.2021. PubMed PMID: 34378991; PMCID: PMC8461816.

23.    Yuan Y, Xu P, Jiang Q, Cai X, Wang T, Peng W, Sun J, Zhu C, Zhang C, Yue D, He Z, Yang J, Zeng Y, Du M, Zhang F, Ibrahimi L, Schaul S, Jiang Y, Wang J, Sun J, Wang Q, Liu L, Wang S, Wang L, Zhu X, Gao P, Xi Q, Yin C, Li F, Xu G, Zhang Y, Shu G. Exercise-induced alpha-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation. EMBO J. 2020;39(7):e103304. Epub 2020/02/28. doi: 10.15252/embj.2019103304. PubMed PMID: 32104923; PMCID: PMC7110140.

24.    Shin S*, Pang Y*, Park J, Liu L, Lukas BE, Kim SH, Kim KW, Xu P, Berry DC, Jiang Y#. Dynamic control of adipose tissue development and adult tissue homeostasis by platelet-derived growth factor receptor alpha. Elife. 2020;9. Epub 2020/06/20. doi: 10.7554/eLife.56189. PubMed PMID: 32553115; PMCID: PMC7338051.

25.    Shin S, El-Sabbagh AS, Lukas BE, Tanneberger SJ, Jiang Y#. Adipose stem cells in obesity: challenges and opportunities. Biosci Rep. 2020;40(6). Epub 2020/05/27. doi: 10.1042/BSR20194076. PubMed PMID: 32452515; PMCID: PMC7284323.

26.    Acharya A, Berry DC, Zhang H, Jiang Y, Jones BT, Hammer RE, Graff JM, Mendell JT. miR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19. Genes Dev. 2019;33(19-20):1367-80. Epub 2019/09/07. doi: 10.1101/gad.328955.119. PubMed PMID: 31488578; PMCID: PMC6771383.

27.    Jiang Y*, Berry DC*, Jo A, Tang W, Arpke RW, Kyba M, Graff JM. A PPARgamma transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion. Nat Commun. 2017;8:15926. doi: 10.1038/ncomms15926. PubMed PMID: 28649987.

28.    Jiang Y*, Berry DC*, Graff JM. Distinct cellular and molecular mechanisms for beta3 adrenergic receptor induced beige adipocyte formation. Elife. 2017;6. doi: 10.7554/eLife.30329. PubMed PMID: 29019320.

29.    Berry DC*, Jiang Y*, Arpke RW, Close EL, Uchida A, Reading D, Berglund ED, Kyba M, Graff JM. Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans. Cell Metab. 2017;25(1):166-81. doi: 10.1016/j.cmet.2016.10.023. PubMed PMID: 27889388; PMCID: PMC5226893.
This paper has been highlighted in Nature Reviews Endocrinology.

30.    Berry DC, Jiang Y, Graff JM. Emerging Roles of Adipose Progenitor Cells in Tissue Development, Homeostasis, Expansion and Thermogenesis. Trends Endocrinol Metab. 2016;27(8):574-85. Epub 2016/06/06. doi: 10.1016/j.tem.2016.05.001. PubMed PMID: 27262681.

31.    Berry DC*, Jiang Y*, Graff JM. Mouse strains to study cold-inducible beige progenitors and beige adipocyte formation and function. Nat Commun. 2016;7:10184. doi: 10.1038/ncomms10184. PubMed PMID: 26729601.

32.    Jiang Y*, Berry DC*, Tang W, Graff JM. Independent stem cell lineages regulate adipose organogenesis and adipose homeostasis. Cell Rep. 2014;9(3):1007-22. doi: 10.1016/j.celrep.2014.09.049. PubMed PMID: 25437556; PMCID: 4250841.
a.    This paper has been highlighted in Faculty of 1000.

33.    Atkins M*, Jiang Y*, Sansores-Garcia L, Jusiak B, Halder G, Mardon G. Dynamic rewiring of the Drosophila retinal determination network switches its function from selector to differentiation. PLoS Genet. 2013;9(8):e1003731. Epub 2013/09/07. doi: 10.1371/journal.pgen.1003731. PubMed PMID: 24009524; PMCID: PMC3757064.

34.    Li Y, Jiang Y, Chen Y, Karandikar U, Hoffman K, Chattopadhyay A, Mardon G, Chen R. optix functions as a link between the retinal determination network and the dpp pathway to control morphogenetic furrow progression in Drosophila. Dev Biol. 2013;381(1):50-61. doi: 10.1016/j.ydbio.2013.06.015. PubMed PMID: 23792115; PMCID: PMC3742619.

35.    Jiang Y, Jo AY, Graff JM. SnapShot: Adipocyte Life Cycle. Cell. 2012;150(1):234- e2. Epub 2012/07/10. doi: S0092-8674(12)00775-1 [pii]10.1016/j.cell.2012.06.022. PubMed PMID: 22770223.

36.    Jiang Y, Scott KL, Kwak SJ, Chen R, Mardon G. Sds22/PP1 links epithelial integrity and tumor suppression via regulation of myosin II and JNK signaling. Oncogene. 2011;30(29):3248-60. Epub 2011/03/15. doi: 10.1038/onc.2011.46. PubMed PMID: 21399659; PMCID: PMC3141090.



 

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