2023

Wu R*, Park J*, Qian Y, Shi Z, Hu R, Yuan Y, Xiong S, Wang Z, Yan G, Ong SG, Song Q, Song Z, Mahmoud AM, Xu P, He C, Arpke RW, Kyba M, Shu G, Jiang Q, Jiang Y#. Genetically prolonged beige fat in male mice confers long-lasting metabolic health. Nat Commun. 2023;14(1):2731. Epub 20230512. doi: 10.1038/s41467-023-38471-z. PubMed PMID: 37169793; PMCID: PMC10175245.

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Yuan Y*, Shi Z*, Xiong S*, Hu R, Song Q, Song Z, Ong SG, Jiang Y#. Differential roles of insulin receptor in adipocyte progenitor cells in mice. Mol Cell Endocrinol. 2023:111968. Epub 20230525. doi: 10.1016/j.mce.2023.111968. PubMed PMID: 37244600.

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Benvie AM, Lee D, Steiner BM, Xue S, Jiang Y, Berry DC. Age-dependent Pdgfrbeta signaling drives adipocyte progenitor dysfunction to alter the beige adipogenic niche in male mice. Nat Commun. 2023;14(1):1806. Epub 20230331. doi: 10.1038/s41467-023-37386-z. PubMed PMID: 37002214; PMCID: PMC10066302.

 

Song Q, Chen Y, Ding Q, Griffiths A, Liu L, Park J, Liew CW, Nieto N, Li S, Dou X, Jiang Y, Song Z. mTORC1 inhibition uncouples lipolysis and thermogenesis in white adipose tissue to contribute to alcoholic liver disease. Hepatol Commun. 2023;7(3):e0059. Epub 20230209. doi: 10.1097/HC9.0000000000000059. PubMed PMID: 36757400.

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2022

Torres Irizarry VC, Jiang Y#, He Y#, Xu P#. Hypothalamic Estrogen Signaling and Adipose Tissue Metabolism in Energy Homeostasis. Front Endocrinol (Lausanne). 2022;13:898139. Epub 2022/06/28. doi: 10.3389/fendo.2022.898139. PubMed PMID: 35757435; PMCID: PMC9218066.

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Yuan Y, Zhu C, Wang Y, Sun J, Feng J, Ma Z, Li P, Peng W, Yin C, Xu G, Xu P, Jiang Y, Jiang Q, Shu G. alpha-Ketoglutaric acid ameliorates hyperglycemia in diabetes by inhibiting hepatic gluconeogenesis via serpina1e signaling. Sci Adv. 2022;8(18):eabn2879. Epub 2022/05/05. doi:10.1126/sciadv.abn2879. PubMed PMID: 35507647; PMCID: PMC9067931.

 

Ye H, Feng B, Wang C, Saito K, Yang Y, Ibrahimi L, Schaul S, Patel N, Saenz L, Luo P, Lai P, Torres V, Kota M, Dixit D, Cai X, Qu N, Hyseni I, Yu K, Jiang Y, Tong Q, Sun Z, Arenkiel BR, He Y, Xu P, Xu Y. An estrogen-sensitive hypothalamus-midbrain neural circuit controls thermogenesis and physical activity. Sci Adv. 2022;8(3):eabk0185. Epub 2022/01/20. doi: 10.1126/sciadv.abk0185. PubMed PMID: 35044814; PMCID: PMC8769556.

 

Wang Z, Kim J, Zhang P, Galvan Achi JM, Jiang Y, Rong L. Current therapy and development of therapeutic agents for lung cancer. Cell Insight. 2022;1(2):100015. doi: https://doi.org/10.1016/j.cellin.2022.100015.

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2021

Park J*, Shin S*, Liu L*, Jahan I, Ong SG, Xu P, Berry DC, Jiang Y#. Progenitor-like characteristics in a subgroup of UCP1+ cells within white adipose tissue. Dev Cell. 2021;56(7):985-99 e4. Epub 2021/03/13. doi: 10.1016/j.devcel.2021.02.018. PubMed PMID: 33711247; PMCID: PMC8026751.

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Paris S, Ekeanyanwu R, Jiang Y, Davis D, Spechler SJ, Souza RF. Obesity and its effects on the esophageal mucosal barrier. Am J Physiol Gastrointest Liver Physiol. 2021;321(3):G335-G43. Epub 2021/08/19. doi: 10.1152/ajpgi.00199.2021. PubMed PMID: 34405732.

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Wang Z, Peet NP, Zhang P, Jiang Y, Rong L. Current Development of Glioblastoma Therapeutic Agents. Mol Cancer Ther. 2021;20(9):1521-32. Epub 2021/06/27. doi: 10.1158/1535-7163.MCT-21-0159. PubMed PMID: 34172531.

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Griffiths A, Wang J, Song Q, Iyamu ID, Liu L, Park J, Jiang Y, Huang R, Song Z. Nicotinamide N-methyltransferase (NNMT) upregulation via the mTORC1-ATF4 pathway activation contributes to palmitate-induced lipotoxicity in hepatocytes. Am J Physiol Cell Physiol. 2021. Epub 2021/08/12. doi: 10.1152/ajpcell.00195.2021. PubMed PMID: 34378991.

 

 

2020

Shin S, El-Sabbagh AS, Lukas BE, Tanneberger SJ, Jiang Y#. Adipose stem cells in obesity: challenges and opportunities. Biosci Rep. 2020 Jun 26;40(6). doi: 10.1042/BSR20194076. PubMed PMID: 32452515; PubMed Central PMCID: PMC7284323.

 

Shin S*, Pang Y*, Park J, Liu L, Lukas BE, Kim SH, Kim KW, Xu P, Berry DC, Jiang Y#. Dynamic control of adipose tissue development and adult tissue homeostasis by platelet-derived growth factor receptor alpha. Elife. 2020 Jun 19;9. doi: 10.7554/eLife.56189. PubMed PMID: 32553115; PubMed Central PMCID: PMC7338051.

 

Yuan Y, Xu P, Jiang Q, Cai X, Wang T, Peng W, Sun J, Zhu C, Zhang C, Yue D, He Z, Yang J, Zeng Y, Du M, Zhang F, Ibrahimi L, Schaul S, Jiang Y, Wang J, Sun J, Wang Q, Liu L, Wang S, Wang L, Zhu X, Gao P, Xi Q, Yin C, Li F, Xu G, Zhang Y, Shu G. Exercise-induced α-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation. EMBO J. 2020 Apr 1;39(7):e103304. doi: 10.15252/embj.2019103304. Epub 2020 Feb 27. PubMed PMID: 32104923; PubMed Central PMCID: PMC7110140.

 

 

2019

Acharya A, Berry DC, Zhang H, Jiang Y, Jones BT, Hammer RE, Graff JM, Mendell JT. miR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19. Genes Dev. 2019 Oct 1;33(19-20):1367-1380. doi: 10.1101/gad.328955.119. Epub 2019 Sep 5. PubMed PMID: 31488578; PubMed Central PMCID: PMC6771383.

 

 

2017

Jiang Y, Berry DC, Graff JM. Distinct cellular and molecular mechanisms for β3 adrenergic receptor-induced beige adipocyte formation. Elife. 2017 Oct 11;6. doi: 10.7554/eLife.30329. PubMed PMID: 29019320; PubMed Central PMCID: PMC5667933.

 

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Jiang Y, Berry DC, Jo A, Tang W, Arpke RW, Kyba M, Graff JM. A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion. Nat Commun. 2017 Jun 26;8:15926. doi: 10.1038/ncomms15926. PubMed PMID: 28649987; PubMed Central PMCID: PMC5490270.

 

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Berry DC*, Jiang Y*, Arpke RW, Close EL, Uchida A, Reading D, Berglund ED, Kyba M, Graff JM. Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans. Cell Metab. 2017 Jan 10;25(1):166-181. doi: 10.1016/j.cmet.2016.10.023. Epub 2016 Nov 23. PubMed PMID: 27889388; PubMed Central PMCID: PMC5226893. *Contributed equally to this work.

This paper has been highlighted in Nature Reviews Endocrinology.

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2016

Berry DC*, Jiang Y*, Graff JM. Mouse strains to study cold-inducible beige progenitors and beige adipocyte formation and function. Nat Commun. 2016 Jan 5;7:10184. doi: 10.1038/ncomms10184. PubMed PMID: 26729601; PubMed Central PMCID: PMC4728429. *Contributed equally to this work.

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Berry DC, Jiang Y, Graff JM. Emerging Roles of Adipose Progenitor Cells in Tissue Development, Homeostasis, Expansion and Thermogenesis. Trends Endocrinol Metab. 2016 Aug;27(8):574-585. doi: 10.1016/j.tem.2016.05.001. Epub 2016 Jun 1. Review. PubMed PMID: 27262681.

 

 

2014

Jiang Y, Berry DC, Tang W, Graff JM. Independent stem cell lineages regulate adipose organogenesis and adipose homeostasis. Cell Rep. 2014 Nov 6;9(3):1007-22. doi: 10.1016/j.celrep.2014.09.049. Epub 2014 Oct 23. PubMed PMID: 25437556; PubMed Central PMCID: PMC4250841.

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2013

Atkins M*, Jiang Y*, Sansores-Garcia L, Jusiak B, Halder G, Mardon G. Dynamic rewiring of the Drosophila retinal determination network switches its function from selector to differentiation. PLoS Genet. 2013 Aug;9(8):e1003731. doi: 10.1371/journal.pgen.1003731. Epub 2013 Aug 29. PubMed PMID: 24009524; PubMed Central PMCID: PMC3757064. *Contributed equally to this work.

 

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Li Y, Jiang Y, Chen Y, Karandikar U, Hoffman K, Chattopadhyay A, Mardon G, Chen R. optix functions as a link between the retinal determination network and the dpp pathway to control morphogenetic furrow progression in Drosophila. Dev Biol. 2013 Sep 1;381(1):50-61. doi: 10.1016/j.ydbio.2013.06.015. Epub 2013 Jun 20. PubMed PMID: 23792115; PubMed Central PMCID: PMC3742619.

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2012

Jiang Y, Jo AY, Graff JM. SnapShot: adipocyte life cycle. Cell. 2012 Jul 6;150(1):234-234.e2. doi: 10.1016/j.cell.2012.06.022. PubMed PMID: 22770223.

 

 

2011

Jiang Y, Scott KL, Kwak SJ, Chen R, Mardon G. Sds22/PP1 links epithelial integrity and tumor suppression via regulation of myosin II and JNK signaling. Oncogene. 2011 Jul 21;30(29):3248-60. doi: 10.1038/onc.2011.46. Epub 2011 Mar 14. PubMed PMID: 21399659; PubMed Central PMCID: PMC3141090.

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